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Abstract #1122

Towards QSM Challenge 2.0: Creation and Evaluation of a Realistic Magnetic Susceptibility Phantom

José P. Marques1, Berkin Bilgic2,3,4, Jakob Meineke5, Carlos Milovic6,7, Kwok-shing Chan1, Wietske van der Zwaag8, Renaud Hedouin1, Christian Langkammer9, and Ferdinand Schweser10,11

1Donders Institute for Brain Cognition and Behaviour, Radboud University, Nijmegen, Netherlands, 2Athinoula A. Martinos Centre for Biomedical Imaging, Charlestown, MA, United States, 3Department of Radiology, Harvard Medical School, Boston, MA, United States, 4Harvard-MIT Health Sciences and Technology, MIT, Cambridge, MA, United States, 5Philips Research, Hamburg, Germany, 6Department of Electrical Engineering, Pontificia Universidad Catolica de Chile, Santiago, Chile, 7Biomedical Imaging Center, Pontificia Universidad Catolica de Chile, Santiago, Chile, 8Spinoza Centre for Neuroimaging, Amsterdam, Netherlands, 9Department of Neurology, Medical University of Graz, Graz, Austria, 10Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, United States, 11Center for Biomedical Imaging, Clinical and Translational Science Institute, University at Buffalo, The State University of New York, Buffalo, NY, United States

We present the creation of a modular and realistic digital phantom to serve as a ground-truth to assess the quality of different reconstruction algorithms for Quantitative Susceptibility Mapping (QSM). The phantom is derived from high-resolution, quantitative MRI data of a healthy volunteer, features a realistic morphology including a non piece-wise constant susceptibility distribution. Varying degrees of complexity can be realized, for example by adding the effects of tissue microstructure, down sampling or adding background-fields. The freely available phantom will be used in the upcoming QSM Reconstruction challenge.

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