Abstract #3295

Quantification of venous structures in the hippocampus using segment co-registered 7T susceptibility and structural images: First application to focal temporal lobe epilepsy

Rebecca Emily Feldman¹, Alexandru L Rus², Lara V Marcuse³, John W Rutland¹, Madeline C Fields⁴, Bradley N Delman⁵, and Priti Balchandani⁵

¹Radiology, Translational and Molecular Imaging Institute, New York, NY, United States, ²Icahn School of Medicine at Mount Sinai, New York, NY, United States, ³Neurology, Mount Sinai Hospital, New York, NY, United States, ⁴Mount Sinai Hospital, New York, NY, United States, ⁵Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States

Susceptibility-weighted imaging offers superior contrast between veins and surrounding tissue. Our technique to isolate and quantify vein-like objects on SWI, combined with hippocampal segmentation of T1-weighted images, permits characterization of vascular density in focal temporal lobe epilepsy. We found difference in vascular density of both epilepsy patients (16%) and controls (30%), with diminished density on the left in both groups.

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