T1 weighted SPACE has gain popularity in intracranial wall imaging, but its long scan time makes it impractical and its multiple parameters make it very difficult to be optimized. In this study, we looked into the effect of various imaging parameters of T1w SPACE on the signal-to-noise (SNR) and contrast ratio (CR) between vessel wall and cerebrospinal fluid using Bloch equation simulation. An optimized whole-brain intracranial artery wall imaging protocol which had comparable higher CR and SNR within 8min and 0.55mm iso resolution was found. The simulation results were verified by the volunteer study and matched the experiments well.
This abstract and the presentation materials are available to members only; a login is required.