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Abstract #1752

Population averaged ferret brain templates for in-vivo and ex-vivo anatomical and diffusion tensor MRI

Elizabeth B Hutchinson1,2,3, Susan Schwerin3,4, Kryslaine Radomski4, Neda Sadeghi1,2, Michal Komlosh2,3, Jeffrey Jenkins1,2,3, Okan Irfanoglu1,2,3, Sharon Juliano4, and Carlo Pierpaoli1,2

1Quantitative Medical Imaging Section, NIBIB, NIH, Bethesda, MD, United States, 2SQITS/NICHD, NIH, Bethesda, MD, United States, 3Henry M. Jackson Foundation, Bethesda, MD, United States, 4APG, Uniformed Services University of the Health Sciences, Bethesda, MD, United States

In-vivo and Ex-vivo anatomical MRI and DTI templates were generated for the ferret brain along with region of interest segmentation masks based on known ferret neuroanatomy. Templates were built from multiple ferret brain images for each modality using advanced template building tools including symmetric normalization transformation for structural templates and Diffeomorphic Registration for Tensor Accurate AlignMent of Anatomical Structures (DRTAMAS) for DTI templates. The resulting templates are made available on an interactive web site (mriferretatlas.nichd.nih.gov).

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