We estimated the g-ratio (i.e., the ratio of the inner and the outer diameters of myelinated axons) in-vivo in two different datasets of healthy subjects using diffusion and magnetization data. We used this measure to characterize the organization of the structural connectome and compared it to the information obtained by the streamlines reconstructed using tractography. The g-ratio significantly differentiated hub-related aspects of the connections and subcortico-cortical organization. These preliminary results showed that this measure could provide complementary information to the connectome structure.
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