Abstract #3839
Zone Specific ADC + DCE-MRI Composite Maps to Aid in the Detection and Evaluation of Prostate Cancer
Naira Muradyan 1 , Osama Elbuluk 2 , Baris Turkbey 2 , Sandeep Sankineni 2 , Maria J Merino 3 , Senthil Periaswamy 1 , Marcelino Bernardo 2 , Francois Cornud 4 , and Peter L Choyke 2
1
iCAD, Inc., Nashua, NH, United States,
2
Molecular
Imaging Program, NCI, NIH, Bethesda, MD, United States,
3
Laboratory
of Pathology, NCI, NIH, Bethesda, MD, United States,
4
Tourville
Imaging Centre, Paris, France
This study describes a combined analysis method of
Diffusion Weighted and Dynamic Contrast Enhanced MRI for
prostate imaging, which minimizes the need for separate
evaluation of these sequences. Images of 105 patients
from two sites were used retrospectively to develop and
test the prostate zone-specific composite colormaps,
showing better accuracy than standalone Apparent
Diffusion Coefficient outcome. Such objective display of
combined information, which could be easily added to
routine imaging, may be useful for lesion visualization,
evaluation and minimizing reader variability during
multiparametric prostate imaging.
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