Abstract #3840
Performance of High b-Value DWI in identifying high risk prostate cancer patients
Francesca Mertan 1,2 , Harsh K Agarwal 2,3 , Sandeep Sankineni 2 , Marcelino Bernardo 2,4 , Dagane Daar 2,4 , Maria Merino 2 , Bradford Wood 2 , Peter Pinto 2 , Peter L Choyke 2 , and Baris Turkbey 2
1
Grove City College, Grove City, PA, United
States,
2
National
Institutes of Health, Bethesda, MD, United States,
3
Philips
Research NA, Briarcliff Manor, New York, United States,
4
Leidos
Biomedical Research Inc., Frederic National Laboratory
for Cancer Research, Frederick, MD, United States
ADC maps have been shown to detect and stage prostate
cancer. However, at high b-value (b>800mm/s2) DWI signal
from tumor tissue does not follow the mono-exponential
diffusion decay. Therefore high b-value DWI is typically
accessed as part of prostate MRI reading. In this
abstract we have shown that the performance of high
b-value DWI to detect high risk prostate cancer patients
improves with the increase in b-value and its
performance did not change significantly with the
increase in data acquisition time from 23msec to 102msec
for b≥0s/mm2 DWI. High b-value DWI also performed better
than ADC from b≤750s/mm2.
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