Abstract #3432
Piecewise diffusion tensor estimation for fetal imaging application
Uday Krishnamurthy 1,2 , Ramtilak Gattu 1 , Pavan Kumar Jella 1 , Jaladhar Neelavalli 1,2 , and Ewart Mark Haacke 1,2
1
Department of Radiology, Wayne State
University, Detroit, Michigan, United States,
2
Department
of Biomedical Engineering, Wayne State University,
Detroit, Michigan, United States
Diffusion tensor imaging (DTI) enables us to understand
brain maturation and the development of myelin both in
neonatal and pediatric populations. However, the same
has not been extensively used for in-utero applications,
largely owing to fetal motion. In this study we analyzed
the feasibility of piece wise approach of acquiring the
volume of interest i.e. multiple smaller volumes to
encompass the whole volume, using a short TR single shot
EPI. This approach enables a DTI volume set
(12-directions) to be acquired within 10 secs, which
greatly reduces the possibility of data corruption due
to fetal motion.
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