Abstract #3335
A length and offset varied saturation (LOVARS) CEST MRI: A new tool in early detecting both intracerebral hemorrhage and infarct
Meiyun Wang 1 , Erning Zhang 1 , Carlos Torres 2 , Yan Bai 3 , Xiaowei He 4 , Dapeng Shi 3 , Panli Zuo 5 , Michael T McMahon 6 , Benjamin Schmitt 7 , and Xiaolei Song 8
1
Department of Radiology, Henan Provincial
People's Hospital, Zhengzhou, Henan, China,
2
Department
of Radiology, The Ottawa Hospital, The University of
Ottawa, Ottawa, ON, Canada,
3
Henan
Provincial People's Hospital, Zhengzhou, Henan, China,
4
School
of Information Sciences and Technology, Northwest
University, Xian, Shanxi, China,
5
Siemens
Healthcare, Beijing, China,
6
Dept.
of Radiology, The Johns Hopkins University School of
Medicine, Baltimore, Maryland, United States,
7
Siemens
Ltd Australia, Macquarie Park, Australia,
8
Department
of Radiology, The Johns Hopkins University School of
Medicine, Baltimore, Maryland, United States
This study investigated the capability of a length and
offset varied saturation (LOVARS) chemical
exchange-dependent saturation transfer (CEST) imaging in
early detecting intracerebral hemorrhage (ICH) and
ischemia and proved that LOVARS can identify and
separate ICH and ischemia at the early stage by
demonstrating opposite LOVARS signals. Therefore the
non-invasive LOVARS may be a new MRI technique for the
diagnosis of early stroke and may improve stroke patient
care.
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