Abstract #3241
Biexponential T 1 Relaxation at 7T: Characterization and Impact on T 1 Mapping
James A. Rioux 1 , Ives R. Levesque 1,2 , and Brian K. Rutt 1
1
Radiology, Stanford University, Stanford,
CA, United States,
2
Medical
Physics Unit, and Research Institute of the McGill
University Health Centre, McGill University, Montreal,
QC, Canada
White matter exhibits biexponential relaxation, which is
neglected in T
1
measurements
at low field strengths, but which is a significant
source of variation between reported T
1
values
at high field. If the effect of the shorter T
1
component
can be removed, such that only the longer component is
measured, the resulting T
1
value
will be more reproducible across sites and protocols. We
characterized biexponential relaxation in white matter
at 7T, finding T
1
values
of 1349ms and 57ms, with 11% of signal from the short
component. Based on these values we recommend using
minimum inversion times of 150-200ms in
inversion-recovery-based sequences.
This abstract and the presentation materials are available to members only;
a login is required.
Join Here
