Abstract #2763
Efficient Gradient Calibration based on Diffusion MRI
Irvin Teh 1 , Mahon L Maguire 1 , and Jrgen E Schneider 1
1
Division of Cardiovascular Medicine,
Radcliffe Department of Medicine, University of Oxford,
Oxford, United Kingdom
Diffusion MRI is particularly sensitive to the
calibration of the gradient system. We present a simple
and efficient method for gradient calibration based on
comparing the measured apparent diffusion coefficient
(ADC) in the x, y and z directions in an isotropic
cyclooctane phantom, with known reference values, at a
given measured temperature. Pre-calibration measurements
of ADC differed by up to 8.5x10
-5
mm
2
/s
between directions, leading to an elevated fractional
anisotropy (FA) value of 0.10. Post-calibration values
of ADC and FA were 0.9x10
-5
mm
2
/s
and 0.03 respectively. The calibration also benefits
geometric accuracy as demonstrated with high-resolution
anatomical imaging.
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