Abstract #0009
Understanding Signal Sources of MT Asymmetry and Inhomogeneous MT for Imaging Myelination
Jae-Woong Kim 1 , Seung Hong Choi 2 , and Sung-Hong Park 1
1
Korea Advanced Institute of Science and
Technology, Daejeon, Korea,
2
Seoul
National University, Seoul, Korea
As methods for imaging myelination, we investigated
signal sources of MT asymmetry (MTA) and inhomogeneous
MT (IHMT), both of which utilize asymmetric aspects of
MT spectrum. The phantom study showed similar
specificity of MTA and IHMT to myelination. Under the
same average power and total saturation duration,
however, IHMT was independent of asymmetric shift in
saturation offset frequencies but dependent on duration
of each saturation RF pulse, whereas MTA showed
characteristics opposite to IHMT. Although both IHMT and
MTA may be useful for myelin imaging, further studies
are necessary to understand the signal sources and
sensitivity/specificity of MTA and IHMT.
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