Abstract #2888

Impact of Short-Term Administration of Oral Minocycline, a Repurposed Anti-Neuroinflammatory Agent, on MR and Neuropsychological Biomarkers of MCI and AD

Thao T. Tran¹, Cherise Charleswell¹, Nick O'Dell¹, June Liu¹, Michael Miller², Michael Lindsey³, Brian D. Ross¹

¹Clinical MR, HMRI, Pasadena, CA, United States; ²Webster's Community Pharmacy, Altadena, CA, United States; ³Huntington Memorial Hospital, Pasadena, CA, United States

We demonstrate the impact of minocycline on mild cognitive impairment (MCI) and Alzheimer's disease (AD) by employing quantified MR neuro-imaging (qMRI) and neurospectroscopy (MRS).