Tedros Bezabeh1, Omkar B. Ijare1,
Martin Reed2, Tom Blydt-Hansen2, Ian C.P. Smith1
1National Research Council Institute
for Biodiagnostics,
Urinary
tract infection (UTI) is the most common non-epidemic bacterial infection in
adults and children. Due to the longer diagnostic wait time required for the
gold standard the culture method, dipstick methods are commonly used for
the quick diagnosis of UTI. However, dipstick methods are commonly associated
with false negative and/or false positive results. Therefore, other more
rapid methods are desirable. 1H
NMR based metabolic profiling of urine samples could be valuable in this
regard. Elevated levels of trimethylamine-N-oxide, creatine, and an
unassigned signal at 3.71 ppm have been observed in the urine samples with
UTI compared to the control group.