Abstract #4160

Neurochemical alterations detected in Irritable Bowel Syndrome using 2D L-COSY

Scott Quadrelli^1,2, Gerald Holtmann³, Nicholas Talley², Saadallah Ramadan², and Carolyn Mountford⁴

¹Queensland University of Technology, Brisbane, Australia, ²The University of Newcastle, Newcastle, Australia, ³The University of Queensland, Brisbane, Australia, ⁴Translational Research Institute, Brisbane, Australia

IBS is a characterised intermittent chronic abdominal pain and altered bowel habit in the absence of an organic cause. Neurochemical changes may play a role in the pathophysiology of IBS.

Our pilot studies indicate that in vivo neuro 2D L-COSY monitors alterations to neurochemical pathways associated with IBS.

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