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Abstract #4599

Evaluation of contrast agent dispersion in cerebral arteries using CFD simulations: influence on CBF quantification

Karsten Sommer 1 , Regine Schmidt 1 , Hanns-Christian Breit 1 , Dirk Graafen 1 , and Laura M. Schreiber 1

1 Department of Diagnostic and Interventional Radiology, University Medical Center Mainz, Mainz, Rhineland-Palatinate, Germany

In this contribution we present the CFD simulation of contrast agent transport in a high detailed 3D model of the cerebral arteries. We used the results of the simulations to determine the errors induced by contrast agent dispersion in cerebral blood flow quantification. Contrary to recent studies, our results do not show substantial contrast agent bolus dispersion. Dispersion-related cerebral blood flow errors vary between the different outlets of the 3D model, but are on the whole much smaller than previously predicted.

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