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Abstract #4570

Short- and Long-Term Reproducibility of pCASL Brain Perfusion Imaging at 3T

Xiufeng Li 1 , Lynn E. Eberly 2 , Gulin Oz 1 , Elizabeth R. Seaquist 3 , and Silvia Mangia 1

1 Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, 2 Division of Biostatistics, School of Public Health, University of Minnesota, MN, United States, 3 Division of Endocrinology and Diabetes, Department of Medicine, University of Minnesota, MN, United States

While many studies assessed the reproducibility of ASL, very few studies investigated pCASL reproducibility. More importantly, pCASL reproducibility has not been reported in specific sub-cortical brain regions such as the thalamus and the cerebellum. These regions-of-interest are of particular interest for applications in diabetes9 and neurodegenerative diseases. Here we obtained test-retest data on healthy human subjects to evaluate data variability within and across sessions using a whole-brain pCASL protocol at 3T.

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