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Abstract #4571

Retrospective strategy for reducing respiratory motion artifacts in renal perfusion imaging with arterial spin labeling

Arnaud Guidon 1 , Weiying Dai 2 , and David C. Alsop 2

1 GE Healthcare Global MR Applications and Workflow, Boston, MA, United States, 2 Department of Radiology, Beth Israel Deaconess Medical Center, Boston, MA, United States

Arterial Spin Labeling is well-suited for evaluating patients with renal insufficiency for whom risk of gadolinium-based contrast administration is undesirable. However it is vulnerable to misalignment errors predominantly due to abdominal displacements during respiration. Strategies have previously been proposed either relying on controlled-breathing or navigators. The latter is incompatible with background suppression and the former still requires active patients cooperation. Here, we propose an alternative approach allowing background suppressed Free-Breathing Renal Perfusion imaging with retrospective elastic registration of individual tag and control images and report on its relative robustness for 3 different background suppression levels.

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