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Abstract #4569

Dual-vendor comparison of arterial spin labeling with same labeling and readout modules

Henri JMM Mutsaerts 1 , Matthias JP van Osch 2 , Fernando O Zelaya 3 , Mikjel J Skurdal 4 , Wibeke Nordhy 5 , Yi Wang 6 , Oliver Geier 5 , Aart J Nederveen 1 , Atle Bjrnerud 5 , Danny JJ Wang 6 , and Inge R Groote 5

1 Academic Medical Center, Amsterdam, Netherlands, 2 Leiden University Medical Center, Leiden, Netherlands, 3 Kings College London, London, United Kingdom, 4 Akershus University Hospital, Oslo, Norway, 5 Oslo University Hospital, Oslo, Norway, 6 UCLA, Los Angeles, California, United States

The three major MRI vendors have chosen different implementations of ASL, hampering the validity of cross-vendor comparisons and multi-site studies. The current study compares 3T pseudo-continuous ASL (pCASL) CBF-measurements acquired at two major vendors MRI systems: Philips and Siemens. For this study, pCASL sequences were created with near complete similarity between the two vendor systems. These data indicate that if an identical sequence is used, cross-vendor CBF differences are small. Currently, we are including a third major vendor (GE) in the comparison. Data from the three-vendor comparison will be available by January 2014.

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