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Abstract #4552

Reproducibility of Diffusion Weighted MRI under Active Breathing Coordinator control

Evangelia Kaza 1 , David Collins 1 , Richard Symonds-Tayler 1 , Rafal Panek 1 , and Martin Osmund Leach 1

1 CR-UK and EPSRC Cancer Imaging Centre, Institute of Cancer Research and Royal Marsden Hospital, Sutton, Surrey, United Kingdom

The feasibility of diffusion-weighted (DW) MRI automatically acquired during breath holding enforced by a modified, MR-compatible Active Breathing Coordinator (ABC) system was demonstrated on healthy volunteers. The position of abdominal organs, major vessels and the diaphragm was shown to be reproducible between different measurements under ABC control at the same inhaled air volume and unaffected by changes of non-spatial sequence parameters. The observed repeatability of organ position using the ABC device suggests that DW-MRI with controlled lung volume can be matched to CT images acquired with the same ABC settings and thus support radiotherapy treatment planning.

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