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Abstract #4551

Self correction of blood flow effect for brain-fluctuation MRI

Marina Takatsuji 1 , Toshiaki Miyati 1 , Naoki Ohno 1 , Saori Yoshizawa 2 , Tomohiro Noda 1 , Satoshi Kobayashi 3 , Toshifumi Gabata 3 , and Osamu Matsui 3

1 Division of Health Sciences, Institute of Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan, 2 School of Health Sciences, College of Medical, Pharmeceutical and Health Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan, 3 Department of Radiology, School of Medical Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan

The change of the apparent diffusion coefficient ( ADC)during the cardiac cycle in the brain are affected by the regional cerebral blood flow (rCBF). To evaluate hemodynamic-independent water fluctuaion, we corrected the rCBF effect by using the ECG-triggered single shot diffusion echo planner data itself. We corrected the the changes of ADC (ADC) by the maximum ADC with b=0-200 having the highest correlation with the rCBF. There was no significant correlation between corrected-ADC and eCBF. Corrected-ADC makes it possible to obtain the degree of fluctuation of the water molecules hemodynamic-in the brain.

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