Abstract #4551
Self correction of blood flow effect for brain-fluctuation MRI
Marina Takatsuji 1 , Toshiaki Miyati 1 , Naoki Ohno 1 , Saori Yoshizawa 2 , Tomohiro Noda 1 , Satoshi Kobayashi 3 , Toshifumi Gabata 3 , and Osamu Matsui 3
1
Division of Health Sciences, Institute of
Sciences, Kanazawa University, Kanazawa, Ishikawa,
Japan,
2
School
of Health Sciences, College of Medical, Pharmeceutical
and Health Sciences, Kanazawa University, Kanazawa,
Ishikawa, Japan,
3
Department
of Radiology, School of Medical Sciences, Kanazawa
University, Kanazawa, Ishikawa, Japan
The change of the apparent diffusion coefficient (
ADC)during the cardiac cycle in the brain are affected
by the regional cerebral blood flow (rCBF). To evaluate
hemodynamic-independent water fluctuaion, we corrected
the rCBF effect by using the ECG-triggered single shot
diffusion echo planner data itself. We corrected the the
changes of ADC (ADC) by the maximum ADC with b=0-200
having the highest correlation with the rCBF. There was
no significant correlation between corrected-ADC and
eCBF. Corrected-ADC makes it possible to obtain the
degree of fluctuation of the water molecules
hemodynamic-in the brain.
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