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Abstract #4271

Application of SLIM-MRE on an In-Vivo Murine Model

Allen Q. Ye 1 , Temel K. Yasar 2 , Altaf Khan 2 , Ziying Yin 1 , Dieter Klatt 1 , Thomas J. Royston 1 , and Richard L. Magin 1

1 Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, United States, 2 Department of Mechanical Engineering, University of Illinois at Chicago, Chicago, IL, United States

In this study we have utilized SampLing Interval Modulation (SLIM)-MRE on an in-vivo murine experiment. SLIM-MRE enables acquisition of displacement information in multiple directions without increasing total acquisition time. This enables us to acquire MRE images in one-third of the time compared to conventional MRE, which reduces the health problems that might arise due to prolonged anesthesia on mice and also reduces the image misregistration artifacts that might originate from motion of the internal organs such as the bladder and intestines throughout time.

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