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Abstract #4270

Modes of Shear Waves in Brain MR Elastography

Cemre Ariyurek 1,2 , Yusuf Ziya Ider 1 , Necip Gurler 1 , Safa Ozdemir 1 , Alp Emek 1 , Arif Sanli Ergun 3 , and Ergin Atalar 1,2

1 Department of Electrical and Electronics Engineering, Bilkent University, Ankara, Turkey, 2 National Magnetic Resonance Research Center (UMRAM), Ankara, Turkey, 3 Department of Electrical and Electronics Engineering, TOBB-University of Economics and Technology, Ankara, Turkey

In this study, modes of shear waves that may form during MR elastography of brain are investigated. Results of eigenfrequency simulations indicate that there are eigenmodes that may be excited by actuators at correct frequencies. In the results of frequency domain simulations and human experiments peak displacement(s) are observed at certain frequencies, having similar shear wave patterns to eigenmodes. A shift in the frequency of the peak displacement is observed in simulations when stiffness value of brain is altered. Thus, this method can be used for diagnosing diseases altering stiffness by detecting a frequency shift in peak displacement.

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