Meeting Banner
Abstract #3747

Reproducibility of the 1D-ISIS localized ST experiment for hepatic Pi-to-ATP reaction rate measurement at 7T

Ladislav Valkovic 1,2 , Martin Gajdosk 1 , Marek Chmelk 1 , Wolfgang Bogner 1 , Ivan Frollo 2 , Stephan Gruber 1 , Siegfried Trattnig 1 , and Martin Krssk 1,3

1 High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, 2 Department of Imaging Methods, Institute of Measurement Science, Slovak Academy of Sciences, Bratislava, Slovakia, 3 Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria

Our aim was to test the reproducibility/reliability of the fast 31 P saturation transfer (ST) in vivo at 7T for localized measurement of Pi-to-ATP reaction in the liver. Test-retest measurements of the hepatic ST experiment and a contamination check of the spectra from the surrounding muscles were performed. Our data show only negligible fraction of the abdominal muscle signal in the liver spectra and the test-retest variation was very low. Thus we can conclude that fast ST measurements in the liver at 7T are highly reproducible.

This abstract and the presentation materials are available to members only; a login is required.

Join Here