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Abstract #3668

Quantification of liver perfusion MRI with a time-signal curve fitting method

Lei Wang 1 , Sheng Xie 2 , YongLiang Sun 2 , ZhiYing Yang 2 , Jia Ning 3 , and HuiJun Chen 3

1 China-Japan Friendship Hospital, BeiJing, BeiJing, China, 2 China-Japan Friendship Hospital, BeiJing, China, 3 QingHua University, BeiJing, China

Purpose: To analyze the perfusion measurements of the liver with a simple method and to investigate the correlation of clinical results with parameters. Methods and materials: Patients with various levels of fibrosis underwent perfusion MRI of the liver. The time-intensity curves of MR signal from the perfusion MRI were analyzed by linear fitting in segments. Tin, Tout ,Kup and ratio were measured and compared between the S0-2 group and S3-4 group. Results: A significant difference of each parameter (Tin, Tout, Kup and Ratio) between two groups was detected. Conclusion: The new procedure quantifies the hepatocyte-specific uptake of the contrast agent.

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