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Abstract #3568

3D dynamic contrast-enhanced (DCE) MR renography; Evaluation of image quality and estimation of GFR comparing Kwic and Flash sequences

Eli Eikefjord 1,2 , Erling Andersen 3 , Jan Anker Monssen 4 , Erlend Hodneland 5 , Frank Zoellner 6 , Erik Hanson 7 , Arvid Lundervold 5,8 , and Jarle Tor Rrvik 4,9

1 Haukeland University Hospital (HUH), Bergen, Hordaland, Norway, 2 University of Bergen (UoB), Bergen, Hordaland, Norway, 3 Dept. of Clinical Engineering, HUH, Bergen, Norway, 4 Dept. of Radiology, HUH, Bergen, Norway, 5 Dept. of Biomedicine, UoB, Bergen, Norway, 6 Dept. of Computer Assisted Clinical Medicine, Heidelberg University, Mannheim, Germany, 7 Dept. of Mathematics, UoB, Bergen, Norway, 8 HUS, Bergen, Norway, 9 Dept. of Clinical Medicine, UoB, Bergen, Norway

A reliable and reproducible MR Renography technique may provide valuable information about renal functional status. In this project we studied the relationship between image quality and the ability to estimate GFR reliably, using two different DCE-MRI sequences (Kwic and Flash) in 10 healthy subjects and the same post-processing scheme. The correlation between image quality and accuracy appeared to be strong. Considering the Iohexol-clearance as GFR gold-standard, we found the FLASH sequence to give better GFR-estimates than KWIC. In quantitative MRI image quality should be documented to assure good technical compromises in the design of fast imaging techniques.

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