Abstract #3467
Altered cingulate functional circuits in adolescents with Internet addiction disorder revealed by resting-state fMRI
Fuchun Lin 1 , Yasong Du 2 , Yan Zhou 3 , Jianrong Xu 3 , and Hao Lei 1
1
State Key Laboratory of Magnetic Resonance
and Atomic and Molecular Physics, Wuhan Institute of
Physics & Mathematics, Chinese Academy of Sciences,
Wuhan, Hubei, China,
2
Shanghai
Mental Health Center, Jiao Tong University Medical
School, Shanghai, Shanghai, China,
3
RenJi
Hospital, Jiao Tong University Medical School, Shanghai,
Shanghai, China
Resting-state functional connectivity (rsFC) was used to
investigate seven resting-state functional networks
associated with cingulate subregions (sACC, oACC, dACC,
MCC, dPCC, vPCC and RSC) in adolescent students with
Internet addiction disorder (IAD). These functional
networks involve multiple cortical, subcortical, insula,
parietal regions that are known to engage in emotional
generation and processing, executive attention, decision
making, and cognitive control. Although both the IAD
subjects and controls show similar FC patterns for seven
cingulate subregions, however, IAD had altered
connectivity strength for every cingulate subregion
except the RSC. Moreover, the strength of rsFC between
dPCC and PHG was negatively correlated with SCARED, and
the strength of rsFC between vPCC and SFG was negatively
correlated with YIAS. Our findings suggest that rsFC may
be used as a qualified biomarker to understand the
underlying neural mechanisms or to evaluate the
effectiveness of specific early interventions in IAD.
This abstract and the presentation materials are available to members only;
a login is required.
Join Here
