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Abstract #3165

Direct 31 P Magnetic Resonance Imaging Applying the Nuclear Overhauser Effect

Kristian Rink 1 , Moritz C. Berger 1 , Andreas Korzowski 1 , Peter Bachert 1 , and Armin M. Nagel 1

1 German Cancer Research Center (DKFZ), Heidelberg, Germany

Phosphorus plays a crucial role in the energy metabolism of the human body but in comparison to 1 H MRI the in-vivo signal is four orders of magnitude smaller. In this work phosphocreatine images of the human calf muscle at 3T were acquired using a frequency selective 3D imaging sequence amplified by Nuclear Overhauser Effect (NOE) pulses. Implementing the NOE yields an SNR gain of up to 1.4 in-vivo and 1.7 in phantom studies with an isotropic resolution of 1cm (TA=33min).

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