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Abstract #2843

A study of Lactobionic acid coated GdEuO 3 nanoparticles as MRI-FI dual imaging agent

Wenlong Xu 1 , Badrul Alam Bony 1 , Tirusew Tegafaw Mengesha 1 , Cho Rong Kim 1 , Sung June Kim 1 , Md. Wasi Ahmad 1 , and Gang Ho Lee 1

1 chemistry, Kyungpook National University, Teagu, Korea

In this report, magnetic resonance imaging (MRI), and cell labeling (CL) contrast agent of single-phase mixed DyEuO 3 and HoEuO 3 nanoparticles has been synthesized. They were characterized with XRD, FT-IR, TGA, PL, HRTEM, SQUID magnetometer and MRI instrument. There is no appreciable cytotoxicity up to 500 M concentration. The synthesized nanoparticles were monodisperse with average diameter (d avg ) of 2 nm. Both samples were found to be paramagnetic and emitted strong red fluorescence. From in vivo MRI experiment we found that the negative contrast had been enhancement on mouse liver and kidneys after the injection of nanocolloid.

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