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Abstract #2817

Assessment of bone marrow adipose tissue and glucose metabolism in a whole body MR/PET system: distribution patterns and correlation with anthropometric data

Nina F Schwenzer 1 , Marinus Schmid 1 , Sergios Gatidis 1 , Holger Schmidt 1,2 , Cornelia Brendle 1 , Christian la Fougre 3 , Claus D Claussen 1 , Christina Pfannenberg 1 , and Christina Schraml 1

1 Diagnostic and Interventional Radiology, Dept. of Radiology, University Hospital Tbingen, Tbingen, BW, Germany, 2 Preclinical Imaging and Radiophramacy, Dept. of Radiology, University Hospital Tbingen, BW, Germany, 3 Nuclear Medicine, Dept. of Radiology, University Hospital Tbingen, Tbingen, BW, Germany

Recently introduced whole body MR/PET systems allow for assessment of MR- and PET-information within one examination. Furthermore, characterization of tissue properties is possible with high alignment quality of PET and MRI. In the present study, the composition and glucose utilization of bone marrow throughout the human skeleton in vivo was assessed with respect to the fat content using a simultaneous MR/PET scanner. Additionally, the correlation with anthropometric and endocrinological factors on bone marrow composition and metabolic activity such as age, body mass index and blood glucose level were analyzed.

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