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Abstract #2807

Ferumoxytol labeling of human neural progenitor cells for tracking with MRI in the porcine spinal cord

Jason Lamanna 1,2 , Juanmarco Gutierrez 2 , Lindsey Urquia 2 , Natalia Grin 2 , Jonathan Riley 2 , Jaclyn Espinosa 3 , Thais Buchman 2 , John Oshinski 4 , and Nicholas Boulis 2

1 Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, GA, United States, 2 Neurosurgery, Emory University, Atlanta, GA, United States, 3 Surgery, Emory University, GA, United States, 4 Radiology, Emory University, GA, United States

Clinical investigations of cell-based therapies transplanted in to the spinal cord do not have a reliable method of confirming graft delivery or survival. We demonstrate a straightforward approach to label human neural progenitor cells with ferumoxytol and track them in the spinal cord of a large animal.

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