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Abstract #2641

Recipes of Diffusion Measurements with Oscillating Gradients

Valerij G. Kiselev 1 and Bibek Dhital 1,2

1 Department of Radiology, Medical Physics, University Medical Center Freiburg, Freiburg, Germany, 2 German Cancer Consortium (DKTK), Heidelberg, Germany

We discuss two major challenges of diffusion measurements with oscillating gradients: (i) achieving the highest frequency on preclinical scanners and (ii) performing measurements on human scanners. In order to respond to (i), we propose a ramp that does not compromise the maximal achievable frequency below the hardware limits and show explicitly the parameter range for which this extension is crucial. Other important ingredients of diffusion measurements with oscillating gradient are the relative phase of two gradient trains in the spin echo measurements, fast ramps for low-frequency measurements in human scanners and the optimal total gradient duration.

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