Abstract #2642
Preliminary Results on Measuring Intravoxel Incoherent Motion Using Oscillating Diffusion Gradients
Andreas Wetscherek 1 , Bram Stieltjes 2 , and Frederik Bernd Laun 1,2
1
Medical Physics in Radiology (E020), DKFZ,
Heidelberg, Germany,
2
Quantitative
Imaging Based Disease Characterization (E011), DKFZ,
Heidelberg, Germany
Diffusion experiments using oscillating gradients are
performed. In the pancreas of healthy volunteers, sine
gradients were found to cause larger signal attenuation
than cosine gradients of the same b-value. In addition,
the signal attenuation was found to decrease for the
cosine profile when the number of oscillations was
increased. The experimental findings can be understood
in the picture of temporal diffusion spectroscopy and in
the intravoxel incoherent motion model. The method might
be of particular interest for probing the
microvasculature in organs in which the characteristic
timescale of the incoherent motion is shorter than the
echo time.
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