Abstract #2570
Construction of ground-truth data for head motion correction in diffusion MRI
Jan Hering 1,2 , Peter F. Neher 1 , Hans-Peter Meinzer 1 , and Klaus H. Maier-Hein 1,3
1
Div. Medical and Biological Informatics,
German Cancer Research Center, Heidelberg, Germany,
2
Mannheim
University of Applied Sciences, Mannheim, Germany,
3
Quantitative
Image-based Disease Characterization, German Cancer
Research Center, Heidelberg, Germany
Retrospective head motion correction counts to the most
important post-processing steps in diffusion-weighted
MR. However, due to the missing ground-truth, a
quantitative evaluation of correction algorithms is
possible only to a limited extent. Usage of reference
transforms applied to an already aligned data is
restricted to translation, as the diffusion signal is
not invariant under rotation. We present a novel method
for construction of ground-truth head motion data using
the Fiberfox tool for realistic diffusion-weighted
signal simulation. We further show that the rotation
must not be neglected in motion correction and
evaluation.
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