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Abstract #2571

Improved motion correction using interleaved b=0 volumes and b-vector correction in DTI

Benjamin R Morgan 1 , Wayne Lee 1 , and Margot J Taylor 1,2

1 Hospital for Sick Children, Toronto, Ontario, Canada, 2 University of Toronto, Toronto, Ontario, Canada

Diffusion imaging acquisitions are sensitive to head motion, making the collection of a large number of directions problematic, especially in motion-prone populations, such as children. In this study, we propose splitting long acquisitions into separate, shorter acquisitions and including interleaved b=0 reference volumes to facilitate improved motion and b-vector correction. A novel procedure for preprocessing motion-corrupted data collected in this manner is introduced and compared to the standard eddy correction algorithm. Preliminary evidence, using a series of motion-free and motion-corrupted datasets acquired on one healthy adult, shows an advantage to the proposed technique in fractional anisotropy and principle eigenvector estimation.

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