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Abstract #2258

Differentiation of Malignant from Benign Focal Splenic Lesions: Added Value of Diffusion-Weighted MR Imaging

Jiyoung Hwang 1 , Kyung Mi Jang 2 , Seong Hyun Kim 2 , and Mi Hee Lee 3

1 Department of Radiology, Soonchunhyang University Seoul Hospital, Seoul, Seoul, Korea, 2 Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Seoul, Korea, 3 Radiology, Samsung Medical Center, Sungkyunkwan University, Seoul, Seoul, Korea

Purpose: To evaluate the added value of diffusion-weighted (DW) MR imaging for differentiating between malignant and benign focal splenic lesions. Methods: This study included 53 patients with 11 malignant and 42 benign splenic lesions and who underwent gadoxetic acid-enhanced and DW MR imaging. Qualitative and quantitative analyses were conducted for splenic lesions. Results: All malignant lesions showed a hypovascular progressive enhancement pattern, while hypervascular enhancement patterns were only demonstrated in benign lesions (20, 47.6%) (P<0.05). The mean ADC of malignant lesions was lower than that of benign lesions (P< .001). The addition of DW images to conventional MR images showed a significant improvement for predicting malignant splenic lesions (P < 0.001) Conclusion: The addition of DW imaging to conventional MR imaging improves differentiation of malignant from benign splenic lesions.

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