Abstract #2202
Contrast/SNR optimization for the Imaging of Cationized-Ferritin labeled Glomeruli at 9.4T
Jorge Chacn-Caldera 1 , Raffi Kalayciyan 1 , and Lothar R Schad 1
1
Computer Assisted Clinical Medicine,
University of Heidelberg, Mannheim, Germany
Imaging whole kidney volumes to visualize glomeruli with
MRI requires long acquisition times. Wrong parameters
selection can reduce or even impede the visualization of
the glomeruil. In this work we present quick
measurements of effective transverse relaxation time
(T2*) in the kidney cortex and cationized-ferritin
labeled glomeruli at 9.4T in mouse kidneys. The contrast
between them was also calculated for the whole range of
measured echo times. These measurements can be easily
extrapolated and/or replicated in other systems and
field strengths to facilitate the glomerular imaging,
reduce the scanning times and improve the accuracy and
efficiency of possible glomerular quantifications.
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