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Abstract #2068

Depiction of Multiple Sclerosis Lesions with Zero Echo Time (ZTE) Imaging at 7T

Douglas A. C. Kelley 1 , Angela Jakary 2 , Roland Henry 3 , Sarah J Nelson 2 , and Daniel B Vigneron 2

1 Neuro Apps and Workflow, GE Healthcare, Corte Madera, CA, United States, 2 Radiology and Biomedical Imaging, UCSF, San Francisco, CA, United States, 3 Neurology, UCSF, San Francisco, CA, United States

T1 weighted Zero Echo Time (ZTE) imaging at 7T with phased array coils provides improved depiction of cortical and subcortical multiple sclerosis (MS) lesions and surrounding tissue. In equivalent scan times to conventional methods, the sequence provides more uniform grey-white contrast, allowing improved delineation of cortical structures in addition to providing clear depiction of MS lesions and fast relaxing tissues within the brain. Images acquired with both conventional and ZTE inversion recover prepared sequences in several MS patients are compared.

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