Heterogeneous Structural Connectivity of Default Mode Network in Patients with Autism Spectrum Disorder
Chieh-En Jane Tseng 1 , Yu-Chun Lo 1 , Yu-Jen Chen 1 , Yun-Chin Hsu 1 , Shur-Fen Susan Gau 2 , and Wen-Yih Isaac Tseng 1
Center of Optoelectronic Biomedicine,
National Taiwan University, Taipei, Taiwan,
of Psychiatry, National Taiwan University Hospital,
Abnormalities in functional connectivity have been
reported within the default mode network (DMN) in autism
spectrum disorder (ASD). This study uses diffusion
spectrum imaging tractography to evaluate the white
matter integrity of the white matter fiber tracts
connecting the brain regions of the DMN in ASD.
Differences between ASD and typically developing
controls are subtle but show heterogeneity in structural
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