Meeting Banner
Abstract #1826

The influence of carbon dioxide on brain functional homotopy using resting-state fMRI

Olga Marshall 1 , Jinsoo Uh 2 , Daniel Lurie 3 , Hanzhang Lu 2 , Michael P. Milham 3,4 , and Yulin Ge 1

1 1Radiology/Center for Biomedical Imaging, New York University School of Medicine, New York, NY, United States, 2 2Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Texas, United States, 3 Child Mind Institute, New York, United States, 4 Nathan S Kline Institute for Psychiatric Research, New York, United States

Resting state functional MRI (RS-fMRI) using blood oxygenation level dependent (BOLD) technique is used to evaluate the functional connectivity of the human brain. Brain homotopy (inter-hemispheric coordination) is a fundamental characteristic of the intrinsic functional architecture, which now can be assessed with RS-fMRI. Regional homogeneity (Reho) is another brain characteristic and RS-fMRI measure for local brain synchronization. In this study, we have evaluated how CO2 breathing can influence brain functional homotopy and Reho in healthy brains at rest in order to better understand the physiologic respiratory challenge on global inter-hemispheric and local neighboring neurons functional correlations.

This abstract and the presentation materials are available to members only; a login is required.

Join Here