Neuroimaging with INSIDIR: Integrated Single Inversion and Double Inversion Recovery
Andrew L Alexander 1 and Steven R Kecskemeti 1
Waisman Center, University of Wisconsin,
Madison, WI, United States
An efficient 3D brain imaging pulse sequence was
developed with a pair of inversion pulses that
simultaneously acquire both single inversion recovery
(SIR) and double inversion recovery (DIR) image data.
Sampling was performed using a spoiled gradient echoes
with a 3D radial k-space readout. A sliding window
reconstruction was used to generate multiple image
volumes with different single and double inversion
times. The SIR volumes included a nulled gray matter
frame and a nulled white matter frames and also more
standard T1-weighted contrast. The DIR sampling yielded
a gray matter specific map with nulling of both white
matter and CSF.
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