Meeting Banner
Abstract #1126

Pharmacokinetic modelling of longitudinal dceMRI scans for assessment of tumour growth

Monica Enescu 1 , Amalia Cifor 1 , Veerle Kersemans 2 , Danny Allen 2 , Stuart Gilchrist 2 , John Beech 2 , Sean Smart 2 , Michael A Chappell 1 , and Julia A Schnabel 1

1 Institute of Biomedical Engineering, University of Oxford, Oxford, United Kingdom, 2 Preclinical Imaging Group, University of Oxford, Oxford, United Kingdom

A new model based approach to quantify tumour growth from longitudinal dceMRI images is proposed. Subsequent time points were registered to the first time point using a multichannel registration method based on pharmacokinetic parameter maps. This method was shown to successfully recover tumour growth, on data where the tumour change is small and gradual. We have also investigated whether pharmacokinetic parameters at the first time point can act as a predictor of localized tumour growth.

This abstract and the presentation materials are available to members only; a login is required.

Join Here