Abstract #1095
Quantitative perfusion and diffusion weighted magnetic resonance imaging of pancreatic adenocarcinoma: a pilot study
Hyunki Kim 1 , Pablo Arnoletti 2 , John Christein 1 , Marty Heslin 1 , James Posey 1 , Amol Pednekar 3 , T. Beasley 1 , and Desiree Morgan 1
1
University of Alabama at Birmingham,
Birmingham, AL, United States,
2
Center
for Specialized Surgery, FL, United States,
3
Philips
Medical Systems, WA, United States
Breath-hold DCE-MRI/DWI was applied for 16 patients with
treatment-nave pancreatic adenocarcinoma. The
physiological parameters such as Ktrans, kep and ADC
values in pancreatic tumors, non-tumor adjacent
pancreatic parenchyma (NAP), liver metastases, and
normal liver tissues were quantitated. Ktrans, kep and
ADC values of pancreatic tumors were significantly lower
than those of non-tumor adjacent pancreatic parenchyma.
Thus, the perfusion and diffusion parameters may be
utilized as diagnostic markers for pancreatic cancer
detection.
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