Meeting Banner
Abstract #0833

Evaluation of brain complexity in psychiatric patients using fractal geometry

Letizia Squarcina 1 , Alberto De Luca 2 , Marcella Bellani 1 , Paolo Brambilla 3,4 , Federico E Turkheimer 5 , and Alessandra Bertoldo 2

1 Section of Psychiatry, AOUI Verona, Verona, VR, Italy, 2 Department of Information Engineering, University of Padova, Padova, PD, Italy, 3 University of Udine, Udine, UD, Italy, 4 Dept. of Psychiatry and Behavioral Sciences, University of Texas Medical School, Houston, TX, United States, 5 King's College London, London, United Kingdom

With this study, we used fractal geometry to analyze T1 data of patients affected by schizophrenia or bipolar disorder. We applied the box-count algorithm on segmented data and a modified, local version of it on non-segmented data, to compute fractal dimension both on the whole brain and in substructures. We found a marked difference on fractal dimension values in patients in respect to healthy controls. Fractal dimension is reduced in patients, with a visible effect especially in frontal lobe, which confirms previous findings of modification of this structures in these diseases.

This abstract and the presentation materials are available to members only; a login is required.

Join Here