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Abstract #0367

Amide Proton Transfer and 3D Pseudo-continuous Arterial Spin Labeling MRI in Grading Cerebral Gliomas

Meiyun Wang 1 , Yan Bai 1 , Panli Zuo 2 , Benjamin Schmitt 3 , Dapeng Shi 1 , Jie Tian 4 , and Jinyuan Zhou 5

1 Department of Radiology, Henan Provincial Peopls's Hospital, Zhengzhou, Henan, China, 2 Siemens Healthcare, Beijing, China, 3 Siemens Healthcare, Germany, 4 Institute of Automation, Chinese Academy of Sciences, Beijing, China, 5 Department of Radiology, Johns Hopkins University, Baltimore, MD, United States

This study investigated the value of amide proton transfer (APT) and 3D pseudo-continuous arterial spin labeling (pCASL) MRI in grading gliomas. The results showed a positive correlation between endogenous mobile proteins and CBF in gliomas and suggested that the parameters derived from APT and 3D pCASL MRI are useful in grading cerebral gliomas.

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