Abstract #0368
Sodium ( 23 Na) MR Imaging in Pediatric Astrocytomas
Vincent Kyu Lee 1 , Rafael Ceschin 1 , Yongxian Qian 2,3 , Fernando Boada 4 , James Mountz 5 , Regina Jakacki 6 , Ian Pollack 7 , and Ashok Panigrahy 2
1
Radiology, University of Pittsburgh,
Pittsburgh, Pa, United States,
2
Radiology,
University of Pittsburgh, Pa, United States,
3
Bioengineering,
University of Pittsburgh, Pa, United States,
4
Radiology,
New York University, NY, United States,
5
University
of Pittsburgh, Pa, United States,
6
Pediatrics,
University of Pittsburgh, Pa, United States,
7
Pediatric
Neurosurgery, University of Pittsburgh, Pa, United
States
In this study we report the alterations in sodium
intensity observed in a spectrum of pediatric gliomas
using 23Na MR imaging to characterize the changes.
Pediatric astrocytoma patients (total=26; brainstem
gliomas (n=10), low grade (n=6), and high grade (n=10)
supratentorial gliomas) at different points of therapy
were scanned on clinical 3T MRI scanner. An overall
increase in sodium concentration in the brain tumors
compared to normal appearing grey and white matter is
observed, and the heterogeneous tumor response is
demonstrated in supratentorial gliomas. Overall results
show the viability of sodium scans as a supplement to
clinical scans.
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