Abstract #0118
A Combined High Spatial- and High Angular-Resolution Diffusion MRI Atlas of the Human Brainstem and Thalamus
Evan Calabrese 1 , Christine Hulette 2 , and G. Allan Johnson 3
1
Biomedical Engineering, Duke University,
Durham, North Carolina, United States,
2
Pathology,
Duke University, Durham, North Carolina, United States,
3
Radiology,
Duke University, Durham, North Carolina, United States
Deep brain stimulation (DBS) provides symptomatic relief
from a number of otherwise refractory neurologic
conditions through stimulation of small structures in
the brainstem and diencephalon. As researchers and
clinicians continue to investigate new DBS targets,
there is a need for accurate 3D maps of brainstem
anatomy and structural connectivity. Diffusion MRI can
provide important insight, but clinical studies lack the
spatial and/or angular (diffusion) resolution needed for
detailed mapping. We present a high spatial- and high
angular-resolution diffusion MRI atlas of the postmortem
human brainstem and thalamus with an emphasis on
structural mapping of DBS targets.
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