Abstract #0104
NODDI with dispersion anisotropy
Maira Tariq 1 , Torben Schneider 2 , Daniel C Alexander 1 , Claudia AM Wheeler-Kingshott 2 , and Hui Zhang 1
1
Department of Computer Science & Centre for
Medical Image Computing, University College London,
London, United Kingdom,
2
NMR
Research Unit, Department of Neuroinflammation, UCL
Institute of Neurology, University College London,
London, United Kingdom
We present a clinical technique to estimate the
anisotropy of the orientations distribution of neurites,
using Neurite Orientation Dispersion and Density Imaging
(NODDI) technique. We show that NODDI can be utilised in
vivo with a more realistic description of orientations
of neurites, using a clinically feasible protocol, while
the NODDI technique introduced in the original
publication is still an accurate model for estimating
neurite density and their concentration about the
dominant orientation.
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