Abstract #2060

Evaluation of Multi-shot DTI Metrics at Non-Compressed Levels for the Diagnosis and Prognosis of Degenerative Cervical Myelopathy (DCM)

Sisi Li¹, Ke Wang², Xiao Han³, Jinchao Wang³, Wen Jiang³, Xiaodong Ma⁴, Bing Wu⁵, Yandong Liu³, Wei Liang³, and Hua Guo¹

¹Center for Biomedical Imaging Research, Beijing, China, ²Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA, United States, ³Beijing Jishuitan Hospital, Beijing, China, ⁴University of Minnesota, Minnesota, Minnesota, MN, United States, ⁵GE Healthcare, MR Research China, Beijing, China

Degenerative cervical myelopathy (DCM) is a chronic disease of spinal cord. The sensitivity of conventional structural T1W and T2W MRI to the diagnosis of DCM is low. Diffusion tensor imaging (DTI) can provide quantitative assessments for pre- and post-surgery spinal cord functions. However, the prognostic value of DTI metrics at the level-of-most-compression (LMC) remains controversial. Additionally, it is difficult to differentiate the clinical utility of various tracts at LMC due to severe compressions and limited resolution. This retrospective cohort follow-up study aimed to investigate the correlation of DTI metrics with clinical assessment in different tracts at non-compressed C2 level.

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