Abstract #1847

Velocity-Selective Inversion prepared Arterial Spin Labeling: Examination in a Commercial Perfusion Phantom

Feng Xu^1,2, Dan Zhu³, Hongli Fan^2,3, Hanzhang Lu^1,2, Dapeng Liu^1,2, Wenbo Li^1,2, and Qin Qin^1,2

¹1The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, United States, ²F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States, ³Biomedical Engineering, Johns Hopkins University, Baltimore, MD, United States

Standardized perfusion phantom allows for controlling reproducibility of arterial spin labeling (ASL) techniques across multiple sites, field strength, and vendors. Here using a commercial perfusion phantom, velocity-selective inversion (VSI) prepared ASL was compared with PCASL with an emphasis on velocity-encoding directions. While this effect is amplified on this phantom with feeding channels having only vertical and transverse flow directions, VSI-ASL with a tilted encoding direction achieved higher labeling efficiency through more uniform labeling of the entire feeding tubes. Careful selection of velocity-encoding directions along the major feeding arteries is recommended for VSASL applications to attain optimal labeling efficiency.

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